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by David S. Latchman
Download Gene Regulation : A Eukaryotic Perspective fb2
Biological Sciences
  • Author:
    David S. Latchman
  • ISBN:
    004445242X
  • ISBN13:
    978-0044452423
  • Genre:
  • Publisher:
    Springer; 1990 edition (May 24, 1990)
  • Pages:
    269 pages
  • Subcategory:
    Biological Sciences
  • Language:
  • FB2 format
    1936 kb
  • ePUB format
    1145 kb
  • DJVU format
    1840 kb
  • Rating:
    4.2
  • Votes:
    907
  • Formats:
    lrf mobi azw lit


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Gene regulation is essential for viruses, prokaryotes and eukaryotes as it increases the versatility and adaptability of an organism by allowing the cell . Latchman, David S. (2005). Gene regulation: a eukaryotic perspective.

Gene regulation is essential for viruses, prokaryotes and eukaryotes as it increases the versatility and adaptability of an organism by allowing the cell to express protein when needed. Although as early as 1951, Barbara McClintock showed interaction between two genetic loci, Activator (Ac) and Dissociator (Ds), in the color formation of maize seeds, the first discovery of a gene regulation system is widely considered to be the identification in 1961 of the lac operon, discovered by François Jacob and Jacques Monod, in which some enzymes involved in lactose metabolism.

gene expression during development

The book opens with the central question of how organisms. generate their diversity of cell and tissue types by differential. and combinatorial expression of genes present in an identical. gene expression during development.

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Gene Regulation" provides a view of gene control systems from a eukaryotic standpoint, and tries to redress the bias towards prokaryotic control models. The text explores a variety of regulational strategies and defines their functional significance to the organism as a whole.

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Eukaryotic gene expression is more complex than prokaryotic gene expression because the processes of transcription and translation are physically separated. Unlike prokaryotic cells, eukaryotic cells can regulate gene expression at many different levels.

The second part of the book deals with the role of gene control in specific biological processes

The first part of the book deals with the fundamental processes of gene control at the levels of chromatin structure, transcription, and processes. The second part of the book deals with the role of gene control in specific biological processes. Certain chapters deal with the importance of gene control in cellular signaling processes and for normal development of the embryo.

"Gene Regulation" provides a view of gene control systems from a eukaryotic standpoint, and tries to redress the bias towards prokaryotic control models. The text explores a variety of regulational strategies and defines their functional significance to the organism as a whole. The opening chapters examine the possible processes and mechanisms by which genes could be controlled at different levels, and establish that the key control structures lie at the level of gene transciption. Further chapters continue with an examination of the various steps in transcriptional regulation and explain how events at the molecular level finally have their impact on the biology of the organism via the expression of a diversity of proteins. The final section takes a look at the role of malregulation of gene expression in causing human diseases, particularly in relation to certain forms of cancer. This book should appeal to a wide range of intermediate and advanced students of molecular biology, biochemistry, genetics and clinicians working in these areas.