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by Robert A. Freitas
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Medicine & Health Sciences
  • Author:
    Robert A. Freitas
  • ISBN:
    1570596808
  • ISBN13:
    978-1570596803
  • Genre:
  • Publisher:
    CRC Press; 1 edition (November 1, 1999)
  • Pages:
    509 pages
  • Subcategory:
    Medicine & Health Sciences
  • Language:
  • FB2 format
    1224 kb
  • ePUB format
    1962 kb
  • DJVU format
    1638 kb
  • Rating:
    4.5
  • Votes:
    347
  • Formats:
    mobi mbr doc docx


Robert A. Freitas J. Nanomedicine, Volume I: Basic Capabilities, Landes Bioscience, Georgetown, TX, 1999 .

Capsule Summary of Nanomedicine, Volume I: Nanomedicine, Vol. I: Basic Capabilities (Landes Bioscience, 1999). The first volume of the Nanomedicine book series describes the set of basic capabilities of molecular machine systems that may be required by many, if not most, medical nanorobotic devices, including the physical, chemical, thermodynamic, mechanical, and biological limits of such devices.

Nanomedicine, Volume IIA: Biocompatibility.

Nanomedicine, Volume I: Basic Capabilities

Nanomedicine, Volume I: Basic Capabilities. Once again Robert A. Freitas, Jr. has turned out a remarkable volume of information (similar to Nanomedicine Volume 1). It is probably useful to have read Nanomedicine Volume 1 before reading Volume IIA, but Volume IIA can be read on its own particularly if one has a biological or medical education. Its emphasis is on whether we can expect nanotechnology based devices to be able to operate within the human body but it also deals with whether or not certain aspects of nanotechnology might be dangerous to biological life in general.

Freitas began writing his Nanomedicine book series in 1994. Robert A. Nanomedicine, Volume I: Basic Capabilities (Landes Bioscience, 1999). Volume IIA was published in October 2003 by Landes Bioscience  . Nanomedicine, Vol.

Nanomedicine, Volume I book. Volume I was published in October 1999 by Landes Bioscience while Freitas was a Robert A. .

Nanomedicine, Volume I: Basic Capabilities - Free ebook download as PDF File . df), Text File . xt) or read book . To Nancy, Barbara, and Bob sine qua non Nanomedicine, Volume I: Basic Capabilities, by Robert A. Freitas Jr. 1999 Landes Bioscience

Nanomedicine, Volume I: Basic Capabilities - Free ebook download as PDF File . xt) or read book online for free. 1999 Landes Bioscience. CONTENTS Table of Contents vii List of Figures xiii List of Tables xvii Foreword by K. Eric Drexler xviiii Preface and Acknowledgements xxi Chapter 1. The Prospect of Nanomedicine 1 . A Noble Enterprise 1 . Current Medical Practice 2 . 1 The Evolution of Scientific Medicine 3 . 1 Prehistoric Medicine 3 .

Nanomedicine, Vol. I and II: Basic Capabilities. Robert . Jr. Freitas. Скачать (pdf, . 7 Mb).

Robert A. is currently writing Nanomedicine, the first book to comprehensively . is currently writing Nanomedicine, the first book to comprehensively address the technical issues involved in the medical applications of molecular nanotechnology and medical nanodevice design. Nanomedicine will be published in four volumes. Volume IIA: Biocompatibility was published by Landes Bioscience in October 2003. The anticipated publication date for Volume IIB: Systems and Operations is October 2006.

Nanomedicine, Volume 1: Basic ert A. Nanomedicine, Volume 1: Basic .December 2000 · Kybernetes.

Molecular nanotechnology has been defined as the three-dimensional positional control of molecular structure to create materials and devices to molecular precision. The human body is comprised of molecules, hence the availability of molecular nanotechnology will permit dramatic progress in human medical services. More than just an extension of "molecular medicine," nanomedicine will employ molecular machine systems to address medical problems, and will use molecular knowledge to maintain and improve human health at the molecular scale. Nanomedicine will have extraordinary and far-reaching implications for the medical profession, for the definition of disease, for the diagnosis and treatment of medical conditions including aging, for our very personal relationships with our own bodies and ultimately for the improvement and extension of natural human biological structure and function. This book will be published in three volumes over the course of several years. Readers wishing to keep up-to-date with the latest developments may visit the nanomedicine website maintained by the Foresight Institute (http://foresight.org/Nanomedicine/index.html).

Light out of Fildon
The author seems to cover molecular biology, physics, and engineering with equally impressive expertise. Prior to purchasing this book I thought "How can someone write so much on a field that arguably does not yet exist?" I was surprised at just how much thought has gone into the many facets of nanotechnology and nanomedicine -- regardless of the fact that we do not yet have the ability to implement most of the technology being discussed.
The title is perhaps a bit misleading. I would say this book is just as good a primer on nanotech in general as it is on nanomedicine. Many engineering issues are discussed, including power requirements, communication, heat dissipation, and mechanical strength. And, while many ideas are presented in a biological context (for instance, fluid drag is discussed in the context of navigating the blood stream), the information has applicability to nearly any type of nano-engineering.
The information presented is EXTENSIVELY referenced, and by skipping over the mathematical formulas, should be easily understood by someone with a basic background in biology and/or physics/engineering. I highly recommend this book.
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Ffan
The term nanotechnology is used to describe a variety of nanoscale technologies. Molecular nanotechnology has been defined as the three-dimensional positional control of molecular structure to create materials and devices to molecular precision - the ability to construct objects with atomic-scale control.
The availability of molecular nanotechnology will usher in an unprecedented era of dramatic progress in the way medical care is provided. More than just an extension of "molecular medicine," nanomedicine will employ molecular machine systems to address medical problems, and will use molecular knowledge to maintain and improve human health at the molecular scale. Nanomedicine will have extraordinary and far-reaching implications for the medical profession, for the definition of disease, and for the diagnosis and treatment of medical conditions including aging.
The hallmark of medicine up to the present time has been the establishment of a delicate synergy between the tools of the physician/surgeon and those of nature. In most cases, however, one is forced to concede that we doctors have had to rely chiefly on the bodyÕs own self-repair capabilities. The best example, perhaps, is the recognition that antibiotics will not perform their intended function in the absence of an intact immune system.
The coming ability to carry out targeted medical procedures at the molecular level will bring unprecedented power to the practice of medicine, and promises to dominate medical technology research in the coming decades as much or more than even the Human Genome Project.
Nanomedicine (volume 1) is the first book-length technical discussion of the potential medical applications of molecular nanotechnology and medical nanorobotics. It is meant to help us to frame the research issues that must be addressed, and to develop a knowledge base with which to proceed on the path toward medical nanotechnology.
The author, Robert Freitas Jr., has degrees in physics, psychology, and law, and has written on a diverse set of scientific, engineering, and legal topics, including a NASA feasibility analysis of self-replicating space factories. He later authored the first detailed technical design study of a medical nanorobot ever published in a refereed biomedical journal.
When completed, Nanomedicine will be a three-volume technical work with 31 chapters. Its intended audience is technical and professional people with a serious interest in the future of medical technology. The three volumes build upon each other cumulatively. The first Volume, the subject of this review, describes basic capabilities common to all medical nanodevices, and the physical, chemical, thermodynamic, mechanical, and biological limits of such devices. Its primary audience is physical scientists, chemists, biochemists, and biomedical engineers engaged in basic research. The second Volume, still in progress, deals with aspects of device control and configuration, biocompatibility and safety issues, and basic nanomedical components and simple systems. Its primary audience will be systems and control engineers, research physiologists, clinical laboratory analysts, biotechnologists, and biomedical engineers doing applied research. The third Volume, also in progress, discusses the use of nanomedical technology in clinical medicine. Its primary audience is clinical specialists and clinician-scientists.
Volume I of Nanomedicine, Basic Capabilities, begins with a comprehensive and thoughtful account of the underpinnings of modern medicine. Chapter 1, The Prospect of Nanomedicine, defines the field of nanomedicine and its objectives. Several thought experiments are employed to help the reader develop an intuitive appreciation of time, space, and mechanics in the microworld, where nanorobots will be operating. The goals of our current "molecular medicine" are carefully distinguished from the goals of nanomedicine. The evolution of the concept of nanomedicine and cell repair machines is discussed as the natural culmination of several thousand years of medical discovery and innovation. The chapter finishes with an overview of the entire three volume series.
Since nanomachines cannot yet be built, it is important to establish that such devices are in fact feasible, and that their design, fabrication, and operation violate no physical laws and will obey sound engineering principles. Chapter 2, Pathways to Nanomedicine, begins with a discussion of a number of classical objections to nanotechnology such as quantum mechanics, which after careful consideration, are resolved satisfactorily. Next, precursor technologies to nanotechnology and nanomedicine, such as micromachines/MEMS, telemicrosurgery, and tissue engineering, are briefly considered. This is followed by an introduction to the concept of molecular manufacturing. The chapter concludes with brief descriptions of molecular machine parts, nanocomponents, and nanomaterials. Surgeons and other clinical specialists should have little trouble in following the authorÕs discussion to this point. These chapters, though, are followed by a necessarily terse and detailed elaboration of the set of basic capabilities of molecular machine systems that may be required by medical nanorobotic devices. These latter chapters will be best appreciated by those in biomedical engineering or the physical sciences. The capabilities discussed include the abilities to recognize, sort and transport important molecules (Chapter 3); sense the environment (Chapter 4); alter shape or surface texture (Chapter 5); generate onboard energy to power effective robotic functions (Chapter 6); communicate with doctors, patients, and other nanorobots (Chapter 7); navigate throughout the human body, i.e. determining location within vessels, organs, tissues, or cells (Chapter 8); manipulate microscopic objects and move about inside a human body (Chapter 9); and timekeep, perform computations, disable living cells and viruses, and operate at various pressures and temperatures (Chapter 10).
Many of the concepts presented by Dr. Freitas, if not the underlying premise itself, atomic-scale control, are sure to engender controversy. The implications for the future of medicine, would be profound should the technical and theoretical underpinnings of nanomedicine prove to be correct. Given the current pace of development in nanotechnologies generally, the future of medicine really does appear to be nothing short of awesome. Seen in this context, Nanomedicine by Robert Freitas is a must read. It is the authoritative roadmap to the future of medicine.
Kerry
I'm a research engineer with a major U.S. corporation, and I think that Nanomedicine is an awesome book - Freitas obviously did a huge amount of work in writing this book. It isn't light reading - you need a college-level scientific education to really understand it, but even those without a technical background will appreciate the solid foundation that this provides for the tremendous advances that advanced nanotechnology will make possible. At any rate, if you want to understand the coming nanotechnology revolution in medicine, you must read this book.
I was very surprised by two recent reviewers who gave this excellent book an unfavorable rating. They obviously grossly misunderstood this book, apparently confining their long-term view of nanotechnology's contribution to 21st century medicine to the self-assembly of cleverly functionalized nanoparticles, such as the dendrimers being developed at UofM. Such nanoparticles will undoubtedly be very useful over the next few years, but for those of us who plan to predict to future by making it happen, we welcome Freitas' intricately detailed book. This book (and the series) is a vitally necessary foundation for ongoing research into active nanoscale devices that will incorporate nanoscale sensors, molecule-by-molecule reagent separations, molecular electronics, etc. One critic's comment about the left-handed DNA image on the cover reveals that this "reviewer" has not even opened the book. Freitas' use of the "wrong" DNA image was as purposeful as the humans pictured with seven fingers on the spine. He laments at the "left handed DNA" website ([...]) that "apparently these artistic subtleties have been lost on some readers."