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by Gerhard Vogel,Wolfgang H. Vogel,H. Gerhard Vogel
Download Drug Discovery and Evaluation: Pharmacological Assays (Book with CD-ROM) fb2
Medicine & Health Sciences
  • Author:
    Gerhard Vogel,Wolfgang H. Vogel,H. Gerhard Vogel
  • ISBN:
    3540602917
  • ISBN13:
    978-3540602910
  • Genre:
  • Publisher:
    J. A. Majors Company; Bk&CD-Rom edition (January 15, 1997)
  • Pages:
    757 pages
  • Subcategory:
    Medicine & Health Sciences
  • Language:
  • FB2 format
    1264 kb
  • ePUB format
    1595 kb
  • DJVU format
    1686 kb
  • Rating:
    4.5
  • Votes:
    557
  • Formats:
    mbr lit lrf docx


Gerhard Vogel has published more than 160 papers, mainly on new pharmacological methods, on endocrinology (in particular peptide endocrinology), biomechanics and biochemistry of connective tissue, such as skin and bone, and on other topics.

This reference book contains a comprehensive selection of the most frequently used assays for reliably detecting pharmacological effects of potential drugs, including tests for cardiovascular, analgesic, psychotropic, metabolic, endocrine, respiratory, renal, and immunomodulatory activities. Each of the over 700 assays comprises a detailed protocol with the purpose and rationale of the method, a description of the experimental procedure, a critical assessment of the results and their pharmacological and clinical relevance, and pertinent references.

Drug Discovery and Evaluation book. For practitioners and students. Includes a full-text CD-ROM. Drug Discovery and Evaluation: Pharmacological Assays. Comprehensive reference on 700 of the most frequently used assays for reliably detecting pharmacological effects of potential drugs.

by Gerhard Vogel (Author), Wolfgang H. Vogel (Author) . H. Gerhard Vogel (Author) & 0 more. Vogel (Author), H. Gerhard Vogel (Author). Find all the books, read about the author, and more. ISBN-13: 978-3540602910. Prime Book Box for Kids. Story time just got better with Prime Book Box, a subscription that delivers hand-picked children’s books every 1, 2, or 3 months.

Hans G. Vogel, Wolfgang H. Vogel

Hans G. Vogel. This reference book contains a comprehensive selection of the most frequently used assays for reliably detecting pharmacological effects of potential drugs, including tests for cardiovascular, analgesic, psychotropic, metabolic, endocrine, respiratory, renal, and immunomodulatory activities. Each of the over 700 assays comprises a detailed protocol with the purpose and rationale of the method, a description of the experimental procedure, a critical assessment of the results.

Each assay description is sufficiently outlined and equipped with outstanding literature references. A newly included CD-ROM provides easy identification of tests, guidelines and even legal regulations for animal experiments. Dr. Jürg Gertsch, BioWorld, Issue 2, 2003).

Sunday, 28 July 2013 By Unknown. Drug Discovery and Evaluation Pharmacological Assays by H. GERHARD VOGEL. Effects covered include cardiovascular, analgesic, endocrine, psychotropic, respiratory, renal, and immunomodulatory activities.

Safety aspects were addressed by pharmacological testing of the selected compound in high doses in tests directed at indications other than the intended indication of the new compound. These tests were followed by pharmacokinetic studies, which were mainly aimed at confirming of a suitable half-life time and at oral activity

Автор: Vogel Hans G. Название: Drug Discovery and Evaluation, Pharmacological Assays .

This reference book contains a comprehensive selection of the most frequently used assays for reliably detecting pharmacological effects of potential drugs including cardiovascular, analgesic, endocrine, psychotropic, respiratory, renal, and immunomodulatory activities. Each of the over 700 assays comprises a detailed protocol with the purpose and rationale of the method, a critical assessment of the results and their pharmacological and clinical relevance. Identification of specific tests is facilitated by the enclosed CD-ROM which allows for a quick full-text research. An appendix with guidelines and legal regulations for animal experiments in various countries will help to plan experiments properly in accordance with the welfare of the laboratory animals.

Unnis
I have the 2nd edition of this reference, obtained in 2003. Springer-Verlag and their printers have done a very nice job of making this large (1400-page) book, and they provide a very readable typeset. The text is laid out in numerous short application notes describing different pharmacological assays, and these include sections on the study's purpose, a paragraph on the procedure, another on the approach to interpreting results, a fourth cursory section discussing modifications of the method by others, and a usually generous list of references after that. A big plus, I think, is the inclusion of a CD-ROM that contains an Adobe PDF of the entire text. This is a better medium in which to do searching, especially since the hardcover's printed lookup is set up in such extensive run-in indexing, with numerous cascades of indented em-dashes on subentries that it is really kind of annoying. The Contents list, grouped by organ systems, is a lot more useful.

It's still a difficult call making a decision to recommend a text like this - if you are actively doing pharmacological research, your sources are probably more current at your bench, or in recent journals and meetings. But, the very readable structure, many references, and a useful CD-ROM, suggests Vogel's text as an appealing and well-assembled package for academic and group reference.
Iell
I purchased this to read about Drug Discovery but this is more a technical manual about what chemical processes to use to evaluate drugs. So I was disappointed.
iSlate
The book is a wonderful addition to books on drug evaluation. I feel pharmacologists are getting very few books on this subject. This book can end up the search for such pharmacologists. It will surely boost the research in this field. I hope that this book should reach into hands of every pharmacologists. Whether he/she is a academician or researcher, this book will be a valuable addition to his/her personal library. Each institute conducting research or teaching in pharmacology should also have this book in the library.
Many thanks to the authors and publishers of this books.