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by Dennis Dickson,Roy O. Weller
Download Neurodegeneration: The Molecular Pathology of Dementia and Movement Disorders fb2
Medicine & Health Sciences
  • Author:
    Dennis Dickson,Roy O. Weller
  • ISBN:
    1405196939
  • ISBN13:
    978-1405196932
  • Genre:
  • Publisher:
    Wiley-Blackwell; 2 edition (November 7, 2011)
  • Pages:
    496 pages
  • Subcategory:
    Medicine & Health Sciences
  • Language:
  • FB2 format
    1319 kb
  • ePUB format
    1358 kb
  • DJVU format
    1835 kb
  • Rating:
    4.2
  • Votes:
    436
  • Formats:
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ISBN-13: 978-1405196932. This book will be essential reading for clinicians, neuropathologists and basic neuroscientists who require the firm up-to-date knowledge of mechanisms, diagnostic pathology and genetics of Neurodegenerative diseases that is required for progress in therapy and management.

46 Inherited Amyloidoses and Neurodegeneration: Familial British Dementia and Familial Danish Dementia, 439 Tamas Revesz, Agueda Rostagno, Gordon Plant, Tammaryn Lashley, Blas Frangione, Jorge Ghiso and Janice L. Holton.

ISBN: 978-1-405-19693-2 November 2011 Wiley-Blackwell 496 Pages. View on Wiley Online Library. 46 Inherited Amyloidoses and Neurodegeneration: Familial British Dementia and Familial Danish Dementia, 439 Tamas Revesz, Agueda Rostagno, Gordon Plant, Tammaryn Lashley, Blas Frangione, Jorge Ghiso and Janice L. 47 Neurodegeneration with Brain Iron Accumulation, 446 John E. Duda and Kurt A. Jellinger.

International Society of Neuropathology Series. ISBN: 978-1-4051-9693-2. Authors from the wide field of experts in the International Society of Neuropathology and related disciplines bring together the pathological features of all neurodegenerative diseases.

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By Dennis Dickson, Roy O. Weller . In contrast, this book looks to the future and uses a classification based upon molecular mechanisms, rather than clinical or anatomical boundaries.

Published by Wiley-Blackwell. This book is distinct from other books in that it is structured using molecular pathology mechanisms, as opposed to clinical syndrome or anatomical distribution.

Neoplastic Mimics in Soft Tissue and Bone Pathology. Neurophysiology in Clinical Practice. Study medical photos. Published by Wiley-Blackwell. author {Laksanun Cheewakriengkrai and Serge Gauthier}, year {2012} }.

In contrast, this book looks to the future and uses a classification based upon molecular mechanisms, rather than clinical or anatomical boundaries.

Most textbooks on neurodegenerative disorders have used a classification scheme based upon either clinical syndromes or anatomical distribution of the pathology.  In contrast, this book looks to the future and uses a classification based upon molecular mechanisms, rather than clinical or anatomical boundaries.  Major advances in molecular genetics and the application of biochemical and immunocytochemical techniques to neurodegenerative disorders have generated this new approach. Throughout most of the current volume, diseases are clustered according to the proteins that accumulate within cells (e.g. tau, α-synuclein and TDP-43) and in the extracellular compartments (e.g. β-amyloid and prion proteins) or according to a shared pathogenetic mechanism, such as trinucleotide repeats, that are a feature of specific genetic disorders. Chapters throughout the book conform to a standard lay-out for ease of access by the reader and are written by a panel of International Experts

Since the first edition of this book, major advances have been made in the discovery of common molecular mechanisms between many neurodegenerative diseases most notably in the frontotemporal lobar degenerations (FTLD) and motor neuron disease or amyotrophic lateral sclerosis.

This book will be essential reading for clinicians, neuropathologists and basic neuroscientists who require the firm up-to-date knowledge of mechanisms, diagnostic pathology and genetics of Neurodegenerative diseases that is required for progress in therapy and management.