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by Luke A. J. O'Neill,Andrew Bowie

Luke_A._J._O'Neill Andrew_Bowie Medicine English

Medicine

Author:

Luke A. J. O'Neill,Andrew Bowie
ISBN:

1617371629
ISBN13:

978-1617371622
Genre:

Medical Books
Publisher:

Humana Press; Softcover reprint of hardcover 1st ed. 2001 edition (November 9, 2010)
Pages:

443 pages
Subcategory:

Medicine
Language:

English
FB2 format

1300 kb
ePUB format

1869 kb
DJVU format

1709 kb
Rating:

4.5
Votes:

860
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Luke O'Neill and Andrew Bowie bring together a collection of standard and advanced methods for measuring these powerful agents

Luke O'Neill and Andrew Bowie bring together a collection of standard and advanced methods for measuring these powerful agents. Their readily reproducible techniques range from the assay of interleukin protein and mRNA-using ELISA, FACS, and RT-PCR-to the study of interleukin signal transduction. Newer techniques are also covered, including the analysis of interleukin gene polymorphisms and the use of cDNA microarrays. Many of the assays are geared to specific pathologies, including breast cancer, depression, psoriasis, Grave's disease, migraine, and myocardial infarction.

Interleukin Protocols (Methods in Molecular Medicine). Download (pdf, . 5 Mb) Donate Read. Epub FB2 mobi txt RTF. Converted file can differ from the original. If possible, download the file in its original format.

O’Neill and A. Bowie (Eds) Humana Press, Totowa, New Jersey, 2001, pp. 443 ISBN 0-89603-738-X. Article in logy 28(3):475–476 · April 2003 with 2 Reads. How we measure 'reads'. Cite this publication.

Luke O'Neill and Andrew Bowie bring together in Interleukin Protocols a collection of standard and advanced .

Luke O'Neill and Andrew Bowie bring together in Interleukin Protocols a collection of standard and advanced methods for measuring these powerful agents.

Luke O'Neill and Andrew Bowie bring together a collection of standard and advanced methods for measuring these powerful agents

Luke O'Neill and Andrew Bowie bring together a collection of standard and advanced methods for measuring these powerful agents. Newer techniques are also covered, including the analysis of interleukin gene Luke O'Neill and Andrew Bowie bring together a collection of standard and advanced methods for measuring these powerful agents.

Interleukins are a family of proteins that regulate the maturation, diff- entiation, or activation of cells . More books by Luke A. J. O'Neill. Availability: Usually despatched within 3 weeks. More books by Andrew Bowie.

Antifungal Agents: Methods And Protocols (Methods in Molecular Medicine). Interleukin Protocols (Methods in Molecular Medicine). Erika J. Ernst and P. David Rogers. Category: Медицина, Молекулярная медицина. 5 Mb.

Interleukins are a family of proteins that regulate the maturation, diff- entiation, or activation of cells involved in immunity and inflammation, and belong to a broader family termed cytokines. Collectively these proteins are the key orchestrators of host defense and the response to tissue injury. There are currently 23 different interleukins (numbered from IL-1 to IL-23), although the full extent of the interleukin family will only become clear upon analysis of the human genome sequence. Most important, interleukins are central to the pathogenesis of a wide range of diseases that involve an immune com- nent, including such conditions as rheumatoid arthritis, multiple sclerosis, ulcerative colitis, psoriasis, and asthma. Interleukins have also been imp- cated in other conditions, including cancer, migraine, myocardial infarction, and depression. In essence, when cells are activated by interleukins, a program of gene expression is initiated in the target cell that alters the cell’s phenotype, leading to enhanced immune reactivity, inflammation, and/or proliferation. Interleukins are therefore at the core of the cellular basis for many diseases. They are the subject of intense investigation by biomedical researchers and the targeting or use of interleukins in the clinic is proceeding apace. Approaches such as t- geting IL-4 in asthma or IL-1 in joint disease are being pursued, and it is likely that in the next 5–10 years a number of new therapies based on either inhib- ing or administering interleukins will be available.

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