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by Frances M. Platt,Steven U. Walkley
Download Lysosomal Disorders of the Brain: Recent Advances in Molecular and Cellular Pathogenesis and Treatment fb2
Medicine
  • Author:
    Frances M. Platt,Steven U. Walkley
  • ISBN:
    0198508786
  • ISBN13:
    978-0198508786
  • Genre:
  • Publisher:
    Oxford University Press; 1 edition (March 25, 2004)
  • Pages:
    460 pages
  • Subcategory:
    Medicine
  • Language:
  • FB2 format
    1751 kb
  • ePUB format
    1291 kb
  • DJVU format
    1520 kb
  • Rating:
    4.6
  • Votes:
    775
  • Formats:
    lrf lit azw txt


by Frances M. Platt (Author), Steven U. Walkley (Author). -THE LANCET Neurology.

by Frances M. ISBN-13: 978-0198508786.

By Frances M Platt, Steven U Walkley. This book also reflects the progress of medical science over the 20th century and into the 21st. Oxford: Published by Oxford University Press, 2004, £8. 0 (hardback), pp 430. ISBN 0-19-850878-6. This is a marvellous book. The book also clearly shows the optimism for finding a cure for these otherwise fatal neurological conditions.

This book details recent advances in the molecular and cellular pathologies of these diseases and in the development of. .Frances M. Platt, and Steven U. Walkley. Chapter 3 Clinical aspects and diagnosis. Section II Molecular mechanisms of storage.

After an overview of the biology of the endosomal-lysosomal system and the types of diseases resulting from defects in this system, the book describes in detail the molecular mechanisms of storage, model systems and pathophysiological mechanisms, and finally, new advances toward treatment. Chapter 4 Primary defects in lysosomal enzymes.

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Frances M. Platt, Steven U. Although individually rare, they collectively represent a significant group of diseases that primarily present in early infancy or childhood.

Recent Advances in Molecular and Cellular Pathogenesis and Treatment. Platt and Steven U. This book describes the molecular mechanisms and pathophysiological pathways involved and the potential for.

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Neurons undergoing lysosomal storage, demonstrate the presence of abnormal storage bodies, principally in perikarya and in larger dendrites.

Problems with cellular lysosome function underlie a group of neurological disorders known as the storage diseases. These are inherited disorders, characterized by a failure to control the accumulation of internal cell products resulting in cell death. In recent years major advances in the fields of biochemistry and cell biology have expanded our understanding of these disorders. This book describes the molecular mechanisms and pathophysiological pathways involved and the potential for interventions aimed at treatment.